What Is UthPeak®?
First NMNH with Self-GRAS status for use in
select foods, supplements, & medical foods.
UthPeak® NMNH (Reduced NMN) is a patent-pending crystalline NMNH, a reduced form of nicotinamide mononucleotide (NMN), a potentially more potent NAD+ booster than mainstream market-available NAD+ precursors. UthPeak® NMNH (Reduced NMN) has successfully completed preclinical studies and Phase I clinical trials and is now undergoing Phase II clinical studies to further validate its efficacy in supporting various health benefits.
UthPeak® Clinical Agenda
2023
Toxicology Testing Completed
2024
Phase I Clinical Trial Completed
2025
Phase II - Clinical Trial
In a 90-day double-blind, placebo-controlled, randomized clinical study involving 80 healthy participants, the safety, tolerability, and pharmacokinetics of UthPeak® NMNH (reduced NMN) were assessed. The results indicated promising safety outcomes, alongside a significant increase in NAD+ levels and a decrease in biological age indicators. Participants also reported enhanced emotional well-being and energy support throughout the study duration.
Building on findings from both in vitro and in vivo tests, NMNH (reduced NMN) demonstrates potential health benefits that extend beyond animal models. This will be a primary focus for UthPeak™'s research and development efforts in the upcoming phase II clinical trials scheduled for 2025, highlighting the brand's commitment to scientific advancement in health and wellness.
Anti-Aging
UthPeak® stands at the forefront of anti-aging science as a high-purity form of NMNH, directly elevating NAD+ levels to combat age-related decline and promote cellular repair and resilience
Cardiovascular Health Promoting
UthPeak® is a champion for heart health by directly supporting cardiovascular functions. It contributes significantly to maintaining healthy blood vessels, supporting heart muscle health, and promoting better blood flow.
Energy Boost
UthPeak® enhances mitochondrial function, the energy factories within your cells, ensuring a consistent and long-lasting surge of energy.
Brain Function Enhancement
UthPeak® contributes to improved brain function by improving neuronal energy production and maintenance. This can lead to enhanced cognitive functions, including improved memory, focus, and overall mental clarity.
Sleep Quality Improvement
By supporting cellular health and maintaining proper metabolic balance, UthPeak® contributes to improved sleep quality. Healthier cells and balanced energy levels can help normalize sleep patterns, leading to more restful and restorative sleep.
Weight Management
While direct evidence linking UthPeak® to weight management is still under exploration, its role in regulating metabolism may suggest potential benefits. By supporting metabolic balance, UthPeak® could potentially help manage weight effectively as part of a healthy lifestyle.
UthPeak®, A Patent-Pending Stabilized Form of NMNH (Reduced NMN)
With UthPeak® 's patented crystalline technology spanning 20 countries worldwide, prepare to strategize your brand and product offerings by harnessing tomorrow's health ingredient ROCK STAR. Outshine your competitors by entering the new epoch of super NAD+ boosters.
NMNH Supplement Manufacturing and Supplying Methodology
What EffePharm R&D Director Says About UthPeak®?
"We believe that NMNH (Reduced NMN) could be the next star NAD+ booster. We have observed a great deal of potential in this ingredient through animal models in the lab. If these benefits can be confirmed and extended to human beings, we stand to benefit significantly as an aging population. At EffePharm, we exclusively invest in cutting-edge ingredients with verified benefits because we believe in EFFECTIVE NUTRITION. This is what enables us to lead more fulfilling and creative lives. The global success of Uthever® has demonstrated that our efforts can profoundly impact consumers' lives. We are committed to continuing to create value for users of UthPeak®."
--- Dr. Jianjun YU, EffePharm R&D Director
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Is NAD approved by FDA?Currently, NAD and its precursors, like NMNH and NMN, fall under the category of dietary supplements. The Food and Drug Administration (FDA) doesn’t grant approval to dietary supplements in the same manner it does for pharmaceutical drugs. Instead, it monitors the market for any supplements that might pose safety concerns or make unsubstantiated health claims. Manufacturers are responsible for ensuring their products are safe and that any health claims are supported by evidence. While NAD supplements are available on the market, consumers should look for products from reputable sources to ensure quality and safety.
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Where can I find the published clinical data on NMNH?We are currently conducting a Phase II clinical trial. Our findings from both Phase I and Phase II will be included in our upcoming paper submission. The publication date is yet to be determined; however, we will continue to update the results on our website and social media platforms. Contact us to stay informed.
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Is NMNH the same as NMN?NMNH (Reduced Nicotinamide Mononucleotide) and NMN (Nicotinamide Mononucleotide) are related but distinct compounds involved in the body's NAD+ biosynthesis pathway. NMNH is the reduced form of NMN, meaning it has undergone a bio-reduction reaction that changes its molecular structure. NMNH is metabolized through a different, NRK and NAMPT-independent, pathway, which potentially enhances NMNH's ability to increase NAD+ levels to a much higher extent and faster than NMN. While both are precursors to NAD+ and share the goal of boosting NAD+ levels within the body, their differences in chemical structures influence their stability and effectiveness in supplement forms.
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Are there any dangers taking NAD supplements?Like with any supplement, there can be risks associated with taking NAD supplements, especially if taken inappropriately or in excessive amounts. Potential dangers could include interactions with medications, underlying health conditions, or side effects such as nausea, fatigue, and headaches in some individuals. However, when used under the guidance of a healthcare professional and within recommended dosages, NAD supplements are generally considered safe for most people. It's crucial to consult with a healthcare provider before starting any new supplement regimen.
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Are NMNH self-GRAS approved?UthPeak® NMNH (Reduced NMN) is the first NMNH brand to receive self-GRAS approval, meaning it has been assessed by a scientific expert committee for safety. It is now recognized as safe for use in selected conventional foods, dietary supplements, and medical foods.
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How do NMNH and NMN affect NAD+ levels?NMNH (Reduced NMN) and NMN both help increase NAD+ levels in the body, but they do so in slightly different ways. NMN directly boosts NAD+ through the salvage pathway, a process where existing NAD+ is recycled. In contrast, NMNH's reduced form may enable additional or more efficient pathways to elevate NAD+ levels. However, more research is needed to fully understand how NMNH is metabolized and how it compares to NMN in effectiveness.
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Can NMNH be obtained through diet?Currently, NMNH is not typically obtained through diet. It is developed and administered as a supplement, primarily due to its specific molecular structure that is not readily available in dietary sources. As a specialized compound, NMNH is usually manufactured through a controlled process to ensure its efficacy and purity for supplemental use.
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Are there any side effects of NMNH vs NMN?NMNH (reduced NMN) and NMN are generally regarded as safe, backed by findings from completed toxicology and clinical studies. As NAD+ supplements, they are typically safe for daily use. However, potential side effects may include nervousness, headaches, and fatigue. It is crucial to consult with a healthcare provider to establish the correct dosage and usage guidelines.
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What are the implications of the difference between NMNH and NMN?NMNH (Reduced NMN) and NMN are distinct chemical compounds, but both can effectively raise NAD+ levels. Our ongoing clinical studies indicate that NMNH (Reduced NMN) may play a significant role in reducing biological age markers and offering other potential advantages.
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Are NMNH and NMN the same thing?NMNH (Reduced NMN) and NMN (Nicotinamide Mononucleotide) are distinct chemical compounds. NMNH is the reduced form of NMN, differing in its chemical structure by the addition of a hydrogen atom.
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Can NMNH impact multiple tissues and organs?Indeed, NMNH can impact multiple tissues and organs. Its ability to increase NAD+ levels is not limited to a single type of tissue or organ. NMNH has been observed to enhance NAD+ levels in a variety of tissues, including the heart, brain and muscle, indicating its potential for widespread cellular support.
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What makes UthPeak® NMNH unique in the market?UthPeak® NMNH boasts an advanced, patent-pending crystalline form, offering higher purity and stability compared to standard NMN supplements. This distinctive characteristic ensures it delivers enhanced and sustained NAD+ boosting effects, positioning UthPeak® as a frontrunner in the NAD+ supplement market.
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How long does the NAD+ boost from UthPeak® NMNH last?UthPeak® NMNH is notable for its longevity. It raises NAD+ levels for up to 6 hours and maintains them at a high level for about 24 hours. This extended duration surpasses that of many other NAD+ precursors, offering prolonged benefits for users.
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How does UthPeak® NMNH differ from other NAD+ precursors?UthPeak® NMNH sets itself apart from other NAD+ precursors primarily through its exceptional potency. As a reduced form of nicotinamide mononucleotide (NMN), it can increase NAD+ levels up to ten times more effectively than similar compounds. The proprietary crystalline structure of UthPeak® NMNH enhances its stability, ensuring it maintains its integrity and effectiveness in boosting NAD+ levels.
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